Constantinos Stratakis
Adjunct Professor, Pediatrics, Translation Medicine
N/A
N/A
School of Medicine
Adjunct Faculty
Academic Qualifications
| Qualification | Year | Awarding Institution | Department | Thesis title (Optional Entry) |
| MD | 1989 | University of Athens (EKPA) Athens, Greece | School of Medicine | |
| Doctor of Medical Sciences (Didaktorikon) | 1994 | University of Athens (EKPA) Athens, Greece | School of Medicine | Measurement and circadian variation of the IGF growth factors and their binding proteins |
| PhD (hc) | 2012 | Université de Liège | School of Medicine | |
| PhD (hc) | 2018 | University of Athens (EKPA) Athens, Greece | School of Medicine |
Employment History
| Period of employment | Employer | Location | Position | |
| From | To | |||
| July 1st 1990 | June 30th 1996 | Georgetown University | Washington, DC | Intern, resident, fellow, paediatrics, endocrinology and genetics |
| July 1st 1993 | February 28, 2021 | National Institutes of Health (NIH) | Bethesda, MD | Senior Investigator |
| March 1st, 2021 | today |
ELPEN, Inc. & FORTH (www.forth.gr) |
Athens, Greece & Heraklion, Crete, Greece |
CSO, Director, Research Institute & Director of Research |
Publications
| Year | Title | Other authors | Journal and Publisher / Conference |
Vol. | Pages |
| 2000 | Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the carney complex | Kirschner LS, Carney JA, Pack SD, Taymans SE, Giatzakis C, Cho YS, Cho-Chung YS & CA Stratakis | Nature Genetics | 26 | 89-92 |
| 2006 | A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia | Horvath A, Boikos S, Giatzakis C, Robinson-White A, Groussin L, Griffin KJ, Stein E, Levine E, Delimpasi G, Hsiao H-P, Keil M, Heyerdahl S, Matyakhina L, Libe R, Fratticci A, Kirschner LS, Cramer K, Gaillard RC, Bertagna X, Carney JA, Bertherat J, Bossis I & CA Stratakis | Nature Genetics | 38 | 794-800 |
| 2007 | Mutations of the genes coding for the succinate dehydrogenase subunit genes in familial gastrointestinal tumors | McWhinney SR, Pasini B & CA Stratakis | New England Journal of Medicine | 357 | 1054-1056 |
| 2008 | Mutation in PDE8B, a cAMP-specific phosphodiesterase in adrenal hyperplasia | Horvath A, Mericq V & CA Stratakis | New England Journal of Medicine | 358 | 750-752 |
| 2008 | Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone | Tsang KM, Starost MF, Nesterova M, Boikos SA, Watkins T, Almeida MQ, Harran M, Li A, Collins MT, Cheadle C, Mertz EL, Leikin S, Kirschner LS, Robey P & CA Stratakis | Proceedings of the National Academy of Sciences USA | 107 | 8683-8688 |
| 2011 | Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations. | Janeway KA, Kim SY, Lodish M, Nosé V, Rustin P, Gaal J, Dahia PL, Liegl B, Ball ER, Raygada M, Lai AH, Kelly L, Hornick JL; NIH Pediatric and Wild-Type GIST Clinic, O'Sullivan M, de Krijger RR, Dinjens WN, Demetri GD, Antonescu CR, Fletcher JA, Helman L & CA Stratakis | Proceedings of the National Academy of Sciences USA | 108 | 314-318 |
| 2014 | Constitutive activation of PRKACA in adrenal Cushing's syndrome |
Beuschlein F*, Fassnacht M*, Assié G*, Calebiro D*, Stratakis CA*, Osswald A, Ronchi CL, Wieland T, Sbiera S, Faucz F, Schaak K, Schmittfull A, Schwarzmayr T, Barreau O, Vezzosi D, Rizk-Rabbin M, Zabel U, Szarek E, Salpea P, Forlino A, Vetro A, Zuffardi O, Kisker C, Diener S, Meitinger T, Lohse MJ, Reincke M, Bertherat J, Strom TM, Allolio B *first authors |
New England Journal of Medicine | 370 | 1019-1028 |
| 2014 | Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation. | Trivellin G, Daly AF, Faucz FR, Yuan B, Rostomyan L, Larco DO, Schernthaner-Reiter MH, Szarek E, Leal LF, Caberg JH, Castermans E, Villa C, Dimopoulos A, Chittiboina P, Xekouki P, Shah N, Metzger D, Lysy PA, Ferrante E, Strebkova N, Mazerkina N, Zatelli MC, Lodish M, Horvath A, de Alexandre RB, Manning AD, Levy I, Keil MF, Sierra Mde L, Palmeira L, Coppieters W, Georges M, Naves LA, Jamar M, Bours V, Wu TJ, Choong CS, Bertherat J, Chanson P, Kamenický P, Farrell WE, Barlier A, Quezado M, Bjelobaba I, Stojilkovic SS, Wess J, Costanzi S, Liu P, Lupski JR, Beckers A & CA Stratakis | New England Journal of Medicine | 371 | 2363-2374 |
| 2018 | Activating PRKACB somatic mutation in cortisol-producing adenomas | Espiard S, Knape MJ, Bathon K, Assié G, Rizk-Rabin M, Faillot S, Luscap-Rondof W, Abid D, Guignat L, Calebiro D, Herberg FW, Stratakis CA, Bertherat J. | Journal of Clinical Investigation Insight | 3 | e98296 |
| 2020 | Loss of habenular Prkar2a reduces hedonic eating and increases exercise motivation | London E, Wester JC, Bloyd M, Bettencourt S, McBain CJ, Stratakis CA | Journal of Clinical Investigation Insight | 5(23) | e141670 |
Exhibitions
Research Projects
| Ref. Number | Date | Title | Funded by | Project Role* |
| Z01 HD008920: | 1995-2021 | Molecular genetics of endocrine tumors and related disorders | NIH | Principal Investigator |
Academic Consulting Services/Councils/Boards/Editorial Committees
| Ref. Number | Period | Organization | Title of Position or Service | Key Activities |
| 1 | 2017-2020 | SPR | Executive Council | Running the Society for Pediatric Research |
| 2 | 2019-2020 | SPR | President | The head of the Society for Pediatric Research |
| 3 | 2017-today | Molecular & Cellular Endocrinology | Co-Editor-in-Chief | Leading along with 3 other co-editors one of the most respected journals in endocrinology |
| 4 | 2015-today | Hormone & Metabolic Research | Co-Editor-in-Chief | Editing along with 2 other co-editors one of the leading journals in clinical endocrinology |
| 5 | 2021 | Sync, Inc | Chair, Scientific Advisory Board | Leading the science of one of the most important Greek-owned companies in life sciences |
Awards/International Recognition
| Ref. Number | Date | Title | Awarded by: |
| 1 | 1999 | Endocrine Society (USA)-Pharmacia Award for Excellence in Published Clinical Research | (USA) Endocrine Society |
| 2 | 2009 | Ernst Oppenheimer Award | (USA) Endocrine Society |
| 3 | 2000, 2005, 2007 | NIH MERIT AWARDS | (USA) National Institutes of Health |
| 4 | 2015 | NICHD, NIH MENTOR OF THE YEAR | (USA) National Institutes of Health |
| 5 | 2016 | Distinguished Physician 2016 Award | Hellenic Medical Society of New York |
| 6 | 2013 | Honorary Doctorate (PhD) | University of Liege, Belgium |
| 7 | 2018 | Honorary Doctorate (PhD) | University of Athens, Greece |
| 8 | 2018 | International Award for Excellence in Pediatric Endocrinology | European Society for Pediatric Endocrinology (ESPE) |
| 9 | 2019 | Honorary Member | Hellenic Endocrine Society |
| 10 | 2019 | DALE Medal | (UK) Society for Endocrinology |