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Panagiotis Politis

Visiting Professor, Genetics and Cell Biology, Biochemistry

[email protected]

N/A

School of Medicine

Visiting Professor - Frankfurt

Academic Qualifications

Qualification Year Awarding Institution Department Thesis title (Optional Entry)
PhD 2000 University of Oxford Biochemistry The Role of Chromatin in the Regulation of PHO5 and PHO3 Genes in Saccharomyces cerevisiae.
NASA Planetary Biology Internship 1998 Salk Institute for Biological Studies Origins of life  
BSc 1996 University of Patras Biology  

Employment History

Period of employment Employer Location Position
From To
01/2015 date Biomedical Research Foundation of the Academy of Athens (BRFAA) Athens, Greece Principal Investigator – Assistant Professor Level
01/2007–12/2014 12/2014 Biomedical Research Foundation of the Academy of Athens (BRFAA) Athens, Greece Principal Investigator – Lecturer Level
05/2001 12/2006 Hellenic Pasteur Institute Athens, Greece Post-Doctoral Fellow

Publications

Year Title Other authors Journal and Publisher /
Conference		 Vol. Pages
2019 Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients Maximilianos Elkouris, Georgia Kouroupi, Alexios Vourvoukelis, Nikolaos Papagiannakis, Valeria Kaltezioti, Rebecca Matsas, Leonidas Stefanis, Maria Xilouri Frontiers in Cellular Neuroscience In press  
2018 Targeting Long Non-Coding RNAs in Nervous System Cancers: New Insights in Prognosis, Diagnosis and Therapy Malissovas N, Ninou E, Michail A, Current Medicinal Chemistry In press  
2017 Nuclear receptors in neural stem/progenitor cell homeostasis Gkikas D, Tsampoula M Cellular and Molecular Life Sciences 74 4097-4120
2017 Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease Kouroupi G, Taoufik E, Vlachos IS, Tsioras K, Antoniou N, Papastefanaki F, Chroni-Tzartou D, Wrasidlo W, Bohl D, Stellas D, Vekrellis K, Papadimitriou D, Stefanis L, Bregestovski P, Hatzigeorgiou AG, Masliah E, Matsas R. Proc Natl Acad Sci U S A 114 E3679-E3688
2016 Nuclear receptor NR5A2 controls neural stem cell fate decisions during development Stergiopoulos A Nature Communications 7 12230
2014 Prox1 regulates Olig2 expression to modulate binary fate decisions in spinal cord neurons Kaltezioti V, Antoniou D, Stergiopoulos A, Rozani I, Rohrer H The Journal of Neuroscience 34 15816-15831
2013 Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A Foskolou IP, Stellas D, Rozani I, Lavigne MD Oncogene 32 947-960
2010 Prox1 regulates the Notch1-mediated inhibition of neurogenesis Kaltezioti V, Kouroupi G, Oikonomaki M, Mantouvalou E, Stergiopoulos A, Charonis A, Rohrer H, Matsas R PLoS Biology 8 e1000565
2007 BM88/Cend1 regulates cell cycle exit and differentiation of neuronal precursors Makri G, Thomaidou D, Geissen M, Rohrer H, Matsas R Proc Natl Acad Sci U S A 104 17861–17866
2004 Precise nucleosome positioning and the TATA box dictate requirements for histone H4 tail and the bromodomain Bdf1 Martinez-Campa C, Politis P, Moreau JL, Kent N, Goodall J, Mellor J and Goding CR Molecular Cell 15 69-81

Exhibitions

Research Projects

Date Title Funded by Project Role*
12/2017 – to date Investigation into the pathophysiology of anti-GAD65 auto-antibodies in neurological diseases Empeirikeion Co-Principal Investigator
03/2017 – to date Unraveling the role of a novel regulatory mechanism for alternative splicing in brain development Fondation Sante Grant in Biomedical Sciences Scientific/Project Coordinator
2/2014 – 6/2016 Unraveling the role of a novel gene regulatory network in neural development “Excellence” grant scheme from Greek Secretariat of Research and Technology Scientific/Project Coordinator
1/2014 - 1/2016 The role of long non-coding RNAs in mammalian brain development Fondation Sante Grant in Biomedical Sciences Scientific/Project Coordinator
9/2012 - 8/2015 Role of Chaperone-Mediated Autophagy in the nervous system in health and disease “Excellence” grant scheme from Greek Secretariat of Research and Technology Co-Principal Investigator
9/2012 - 30/8/2015 Understanding and predicting renal fibrosis “Excellence” grant scheme from Greek Secretariat of Research and Technology Co-Principal Investigator
06/2013 - 05/2015 The functionality and renewal of pancreatic β-cells: the role of Liraglutatide “SYNERGASIA II” grant from Greek Secretariat of Research and Technology. Co-Principal Investigator
12/2012 - 11/2015 Heterogeneity of autoimmune diseases: understanding of disease specific and patient-specific mechanisms “Thalis” grant from Greek Secretariat of Research and Technology Co-Principal Investigator
7/2010 - 7/2015 Brain Extracellular Matrix in Health and Disease (ECMNET) COST action bm2001, from FP7, EU funds Co-Principal Investigator
12/2009 - 12/2010 The role of Prox1 in the proliferation versus differentiation decisions in neural stem cells during embryonic development IKYDA grant programme 2009, for the exchange and scientific cooperation between Greece and Germany Scientific/Project Coordinator

Academic Consulting Services/Councils/Boards/Editorial Committees

Period Organization Title of Position or Service Key Activities
10-12/11/2017 68th conference of Hellenic Society of Biochemistry and Molecular Biology (HSBMB) Member of the organizing committee  Conference organization
7-10/10/2015 FENS (Federation of European Neuroscience Societies) Featured Regional Meeting Organized (co-Chair) the Symposium: “Transcriptional regulation of neuronal identity” in the FENS (Federation of European Neuroscience Societies) Featured Regional Meeting Conference organization
1-3/11/2012 Hellenic Society for Neuroscience Chair of the Organizing Committee of the annual Conference of the Hellenic Society for Neuroscience Conference organization

Awards/International Recognition

Date Title Awarded by:
25/06/2008 Fulbright Research Scholar Fellowship Fulbright Organization
10/1998–09/2000 Florey EPA studentship during PhD thesis The Queen’s College, University of Oxford, UK
07/2000 Young Scientist Travel Award for the 18th International Congress of Biochemistry and Molecular Biology, Beyond the Genome, International Society of Biochemistry and Molecular Biology
07/1999 Award from the International Society for the Study of the Origin of Life (ISSOL) in the 12th International conference, Origin of Life & 9th ISSOL Meeting, San Diego, USA ISSOL, USA
06/1999 Award from the Florey EPA Fund The Queen’s College, University of Oxford, UK
08/1998 NASA Planetary Biology Fellowship NASA, CA, USA
05/1997 Queen’s association 650th anniversary trust fund Research Award The Queen’s College, University of Oxford, UK

Other Achievements